基于3H智能管理模式的有氧运动在中青年高血压患者中的应用研究

Application of aerobic exercise based on 3H intelligent management mode in young and middle-aged patients with hypertension

摘要:

目的 探讨基于3H(中心医院、社区医院、家庭)智能管理模式的有氧运动干预对中青年高血压患者的应用效果。方法 选取2021年1月至2022年1月保定市第一中医院收治的354例中青年高血压患者为研究对象，按干预方式分为对照组(n=170)和干预组(n=184)。对照组进行常规降压治疗，干预组在常规降压治疗基础上，由医生根据平台数据制定个体化有氧运动处方。比较两组干预前及干预3、6个月后动脉血管病变指标[颈-股动脉脉搏波传导速度(CF-PWV)、肱-踝动脉脉搏波传导速度(BA-PWV)、踝臂指数(ABI)、颈动脉内中膜厚度(IMT)]、血压指标[收缩压(SBP)、舒张压(DBP)]和生化指标[总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、血清胰岛素(INS)、正五聚蛋白3(PTX3)、内源性分泌型糖基化终末产物受体(esRAGE)]。比较两组血压达标率及安全性指标。结果 干预6个月后，干预组血压达标率(84.24%)高于对照组(50.59%)(P<0.05);干预组CF-PWV、BA-PWV、IMT、SBP、DBP、TC、TG、LDL-C、FBG、2 h PBG、INS、PTX3指标均低于对照组(P<0.05)。两组运动相关不良事件发生率比较，差异无统计学意义(P>0.05)。结论 基于3H智能管理模式联合有氧运动可有效改善中青年高血压患者血压水平、动脉血管功能及代谢指标，提升其自我管理能力和生活质量。

Abstract:

Objective Toexploretheapplicationeffectofaerobicexerciseintervention basedontheintelligent managementmodeof3H (centralhospital,communityhospitalandhome)onhypertentioninyoungandmiddle-agedpeople. Methods Atotalof354youngandmiddle-agedpatientswithhypertensioninBaodingNo.1HospitalofTraditionalChinese MedicinefromJanuary2021toJanuary2022wereselectedastheresearchobjects.Theyweredividedintoacontrolgroup (n=170)andaninterventiongroup (n=184)accordingtodifferentintervention methods.Bothgroupsreceivedroutine antihypertensivetreatment,andtheinterventiongroupwasadditionallyprescribedaerobicexercisebydoctorsbasedonthe platformdatainformation.Thearterialvascularindices [carotid-femoralpulsewavevelocity (CF-PWV),brachial-ankle pulsewavevelocity (BA-PWV),ankle-brachialindex (ABI),andcarotidintima-mediathickness(IMT)],bloodpressure parameters[systolicbloodpressure(SBP)anddiastolicbloodpressure(DBP)],andbiochemicalprofiles[totalcholesterol (TC),triglycerides (TG),high-densitylipoproteincholesterol(HDL-C),low-densitylipoproteincholesterol(LDL-C), fastingbloodglucose(FBG),2-hourpostprandialbloodglucose(2hPBG),seruminsulin(INS),pentraxin-3(PTX3),and endogenoussecretoryreceptorforadvancedglycationendproducts(esRAGE)]beforeinterventionandat3and6 months post-interventionwerecomparedbetweengroups.Thebloodpressurecontrolrateandsafetyindicators werecompared betweenthetwogroups.Results At6 monthspost-intervention,thebloodpressurecontrolrateintheinterventiongroup was84.24%,whichwashigherthan50.59% inthecontrolgroup (P <0.05).Comparedwiththecontrolgroup,the interventiongroupdemonstratedsuperiorimprovementsinCF-PWV,BA-PWV,IMT,SBP,DBP,TC,TG,LDL-C,FBG 2hPBG,INSandPTX3at6 months post-intervention(P<0.05).Therewasnostatisticallysignificantdifferenceinthe incidenceofexerciserelatedadverseeventsbetweenthetwogroups (P >0.05).Conclusion Theapplicationofplanned aerobicexerciseinterventioninmiddle-agedandyoungpatientswithhypertensionbasedontheintelligentmanagementmode of3Hcaneffectivelyimprovethebloodpressurelevel,arterialvascularfunctionandmetabolicindicators,aswellaspromote self-managementbehaviorofpatientsandimprovetheirqualityoflife.